BDBM50134145 (R)-10-Benzo[1,3]dioxol-5-yl-2-benzyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione::CHEMBL140599

SMILES: Oc1c2Cc3c([nH]c4ccccc34)C(c3ccc4OCOc4c3)n2c(=O)n1Cc1ccccc1

InChI Key: InChIKey=YIGQWHLIDGSBIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50134145 ((R)-10-Benzo[1,3]dioxol-5-yl-2-benzyl-3a,4,9,10-te...) Show SMILES Oc1c2Cc3c([nH]c4ccccc34)C(c3ccc4OCOc4c3)n2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C27H21N3O4/c31-26-21-13-19-18-8-4-5-9-20(18)28-24(19)25(17-10-11-22-23(12-17)34-15-33-22)30(21)27(32)29(26)14-16-6-2-1-3-7-16/h1-12,25,28,31H,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description In vitro inhibitory activity against bovine phosphodiesterase 5				J Med Chem 46: 4533-42 (2003) Article DOI: 10.1021/jm0300577 BindingDB Entry DOI: 10.7270/Q2N015X2
					More data for this Ligand-Target Pair