BDBM50134308 3-Benzyldisulfanyl-2-methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione::CHEMBL121090

SMILES: CN1C(SSCc2ccccc2)C(=O)n2c(cc3ccccc23)C1=O

InChI Key: InChIKey=WKLCOGRHVUZWEH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50134308 (3-Benzyldisulfanyl-2-methyl-2,3-dihydro-pyrazino[1...) Show SMILES CN1C(SSCc2ccccc2)C(=O)n2c(cc3ccccc23)C1=O Show InChI InChI=1S/C19H16N2O2S2/c1-20-17(22)16-11-14-9-5-6-10-15(14)21(16)18(23)19(20)25-24-12-13-7-3-2-4-8-13/h2-11,19H,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibition of [3H]-GGPP incorporation into recombinant human Ha-Ras-CVLL by Geranylgeranyl transferase type I				Bioorg Med Chem Lett 13: 3661-3 (2003) BindingDB Entry DOI: 10.7270/Q2CF9PHX
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50134308 (3-Benzyldisulfanyl-2-methyl-2,3-dihydro-pyrazino[1...) Show SMILES CN1C(SSCc2ccccc2)C(=O)n2c(cc3ccccc23)C1=O Show InChI InChI=1S/C19H16N2O2S2/c1-20-17(22)16-11-14-9-5-6-10-15(14)21(16)18(23)19(20)25-24-12-13-7-3-2-4-8-13/h2-11,19H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into recombinant human Ha-Ras-CVLS by farnesyl transferase				Bioorg Med Chem Lett 13: 3661-3 (2003) BindingDB Entry DOI: 10.7270/Q2CF9PHX
					More data for this Ligand-Target Pair