null
SMILES: COc1cccc2n3c(cc12)C(=O)N(C)CC3=O
InChI Key: InChIKey=AWWNHAJYDMLWLA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50134314 (9-Methoxy-2-methyl-2,3-dihydro-pyrazino[1,2-a]indo...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College of Science Curated by ChEMBL | Assay Description Inhibition of [3H]-GGPP incorporation into recombinant human Ha-Ras-CVLL by Geranylgeranyl transferase type I | Bioorg Med Chem Lett 13: 3661-3 (2003) BindingDB Entry DOI: 10.7270/Q2CF9PHX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50134314 (9-Methoxy-2-methyl-2,3-dihydro-pyrazino[1,2-a]indo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College of Science Curated by ChEMBL | Assay Description Inhibition of [3H]-FPP incorporation into recombinant human Ha-Ras-CVLS by farnesyl transferase | Bioorg Med Chem Lett 13: 3661-3 (2003) BindingDB Entry DOI: 10.7270/Q2CF9PHX | |||||||||||
More data for this Ligand-Target Pair |