BDBM50134524 (E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-allyl]-phenyl}-acrylic acid::CHEMBL123794
SMILES: Cc1cccc(\C=C\Cc2ccccc2\C=C\C(O)=O)c1OCc1ccccc1
InChI Key: InChIKey=SHXKWDFUPJBYSD-PULAQXAZSA-N
Data: 8 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity for human prostanoid EP3 receptor | Bioorg Med Chem Lett 15: 527-30 (2005) Article DOI: 10.1016/j.bmcl.2004.11.051 BindingDB Entry DOI: 10.7270/Q26H4J51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity for human prostanoid EP4 receptor | Bioorg Med Chem Lett 15: 527-30 (2005) Article DOI: 10.1016/j.bmcl.2004.11.051 BindingDB Entry DOI: 10.7270/Q26H4J51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity for human prostanoid EP2 receptor | Bioorg Med Chem Lett 15: 527-30 (2005) Article DOI: 10.1016/j.bmcl.2004.11.051 BindingDB Entry DOI: 10.7270/Q26H4J51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity for human prostanoid EP1 receptor | Bioorg Med Chem Lett 15: 527-30 (2005) Article DOI: 10.1016/j.bmcl.2004.11.051 BindingDB Entry DOI: 10.7270/Q26H4J51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50134524 ((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair |