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SMILES: O=C1NC(=O)c2c1c1c3ccc[nH]c3nc1c1[nH]c3ccccc3c21

InChI Key: InChIKey=FODXHGHYDBIJSQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134576   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1


(Homo sapiens (Human))		BDBM50134576
PNG
(6,7,12,13-tetrahydro-5H-pyrido[3',2':4,5]pyrrolo[2...)
Show SMILES O=C1NC(=O)c2c1c1c3ccc[nH]c3nc1c1[nH]c3ccccc3c21
Show InChI InChI=1S/C19H8N4O2/c24-18-13-11-8-4-1-2-6-10(8)21-15(11)16-12(14(13)19(25)23-18)9-5-3-7-20-17(9)22-16/h1-7H,(H,23,24,25)
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MMDB

NCI pathway
Reactome pathway
KEGG

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PubMed
n/an/a 250n/an/an/an/an/an/a



Lilly Spain S.A.

Curated by ChEMBL


Assay Description
Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbING

Bioorg Med Chem Lett 13: 3835-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z89BTC
More data for this
Ligand-Target Pair