BDBM50134600 CHEMBL3745925

SMILES: Cn1c2nc(NC3CCCCCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O

InChI Key: InChIKey=HQZLFWDMIGHLJC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50134600 (CHEMBL3745925) Show SMILES Cn1c2nc(NC3CCCCCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O Show InChI InChI=1S/C21H22F2N4O2/c1-27-19-13(12-24-21(26-19)25-15-6-4-2-3-5-7-15)10-18(20(27)28)29-17-9-8-14(22)11-16(17)23/h8-12,15H,2-7H2,1H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin)				Bioorg Med Chem Lett 26: 424-8 (2016) BindingDB Entry DOI: 10.7270/Q24T6M6J
					More data for this Ligand-Target Pair