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BDBM50134727 1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-silanyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-1-pyridin-3-yl-ethanol::CHEMBL359385

SMILES: CC(C)(C)[Si](C)(C)O[C@H]1CC[C@@]2(C)C(CCC3C4CC[C@H](C(C)(O)c5cccnc5)[C@@]4(C)CCC23)C1

InChI Key: InChIKey=CPFRYINYUBIIDM-CWNQDKCOSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134727   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
24-sterol C-methyltransferase


(Arabidopsis thaliana)		BDBM50134727
PNG
(1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-silanyl...)
Show SMILES CC(C)(C)[Si](C)(C)O[C@H]1CC[C@@]2(C)C(CCC3C4CC[C@H](C(C)(O)c5cccnc5)[C@@]4(C)CCC23)C1
Show InChI InChI=1S/C32H53NO2Si/c1-29(2,3)36(7,8)35-24-15-17-30(4)22(20-24)11-12-25-26-13-14-28(31(26,5)18-16-27(25)30)32(6,34)23-10-9-19-33-21-23/h9-10,19,21-22,24-28,34H,11-18,20H2,1-8H3/t22?,24-,25?,26?,27?,28-,30-,31-,32?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Cardiff University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT)

J Med Chem 46: 4714-27 (2003)


Article DOI: 10.1021/jm021114j
BindingDB Entry DOI: 10.7270/Q2K073PR
More data for this
Ligand-Target Pair