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BDBM50134734 1-[(3S,10S,17S)-3-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-1-(3-chloro-pyridin-4-yl)-ethanol::CHEMBL145672

SMILES: CC(C)(C)[Si](C)(C)O[C@H]1CC[C@@]2(C)C(CCC3C4CC[C@@H](C4CCC23)C(C)(O)c2ccncc2Cl)C1

InChI Key: InChIKey=DEPMEDSXCRDCRX-ZLQNVTQDSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134734   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
24-sterol C-methyltransferase


(Arabidopsis thaliana)		BDBM50134734
PNG
(1-[(3S,10S,17S)-3-(tert-Butyl-dimethyl-silanyloxy)...)
Show SMILES CC(C)(C)[Si](C)(C)O[C@H]1CC[C@@]2(C)C(CCC3C4CC[C@@H](C4CCC23)C(C)(O)c2ccncc2Cl)C1
Show InChI InChI=1S/C31H50ClNO2Si/c1-29(2,3)36(6,7)35-21-14-16-30(4)20(18-21)8-9-23-22-10-13-26(24(22)11-12-25(23)30)31(5,34)27-15-17-33-19-28(27)32/h15,17,19-26,34H,8-14,16,18H2,1-7H3/t20?,21-,22?,23?,24?,25?,26-,30-,31?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Cardiff University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT)

J Med Chem 46: 4714-27 (2003)


Article DOI: 10.1021/jm021114j
BindingDB Entry DOI: 10.7270/Q2K073PR
More data for this
Ligand-Target Pair