BDBM50134802 (E)-3-{4-[(E)-3-(2-Chloro-phenyl)-3-oxo-propenyl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxy-acrylamide::(E)-3-{4-[3-(2-Chloro-phenyl)-3-oxo-propenyl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxy-acrylamide::3-(4-(3-(2-chlorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide::CHEMBL142441

SMILES: Cn1cc(\C=C\C(=O)c2ccccc2Cl)cc1\C=C\C(=O)NO

InChI Key: InChIKey=HWRSJXRUXNYVBE-CDJQDVQCSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50134802 ((E)-3-{4-[(E)-3-(2-Chloro-phenyl)-3-oxo-propenyl]-...) Show SMILES Cn1cc(\C=C\C(=O)c2ccccc2Cl)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H15ClN2O3/c1-20-11-12(10-13(20)7-9-17(22)19-23)6-8-16(21)14-4-2-3-5-15(14)18/h2-11,23H,1H3,(H,19,22)/b8-6+,9-7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 1B				Eur J Med Chem 43: 621-32 (2008) Article DOI: 10.1016/j.ejmech.2007.05.004 BindingDB Entry DOI: 10.7270/Q28K78V4
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50134802 ((E)-3-{4-[(E)-3-(2-Chloro-phenyl)-3-oxo-propenyl]-...) Show SMILES Cn1cc(\C=C\C(=O)c2ccccc2Cl)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H15ClN2O3/c1-20-11-12(10-13(20)7-9-17(22)19-23)6-8-16(21)14-4-2-3-5-15(14)18/h2-11,23H,1H3,(H,19,22)/b8-6+,9-7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma"La Sapienza" Curated by ChEMBL					Assay Description Inhibitory concentration against maize histone deacetylase 2				J Med Chem 48: 3344-53 (2005) Article DOI: 10.1021/jm049002a BindingDB Entry DOI: 10.7270/Q2222VKN
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50134802 ((E)-3-{4-[(E)-3-(2-Chloro-phenyl)-3-oxo-propenyl]-...) Show SMILES Cn1cc(\C=C\C(=O)c2ccccc2Cl)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H15ClN2O3/c1-20-11-12(10-13(20)7-9-17(22)19-23)6-8-16(21)14-4-2-3-5-15(14)18/h2-11,23H,1H3,(H,19,22)/b8-6+,9-7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma"La Sapienza" Curated by ChEMBL					Assay Description Tested for maize Histone deacetylase 2 inhibitory activity				J Med Chem 46: 4826-9 (2003) Article DOI: 10.1021/jm034167p BindingDB Entry DOI: 10.7270/Q28C9X0G
					More data for this Ligand-Target Pair