BDBM50134804 (E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-phenyl-propenyl)-1H-pyrrol-2-yl]-acrylamide::(E)-N-Hydroxy-3-[1-methyl-4-(3-oxo-3-phenyl-propenyl)-1H-pyrrol-2-yl]-acrylamide::CHEMBL145685::N-hydroxy-3-(1-methyl-4-(3-oxo-3-phenylprop-1-enyl)-1H-pyrrol-2-yl)acrylamide

SMILES: Cn1cc(\C=C\C(=O)c2ccccc2)cc1\C=C\C(=O)NO

InChI Key: InChIKey=ZDBWMZVBCYVNPS-FIFLTTCUSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50134804 ((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-phenyl-pr...) Show SMILES Cn1cc(\C=C\C(=O)c2ccccc2)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H16N2O3/c1-19-12-13(11-15(19)8-10-17(21)18-22)7-9-16(20)14-5-3-2-4-6-14/h2-12,22H,1H3,(H,18,21)/b9-7+,10-8+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 1B				Eur J Med Chem 43: 621-32 (2008) Article DOI: 10.1016/j.ejmech.2007.05.004 BindingDB Entry DOI: 10.7270/Q28K78V4
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50134804 ((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-phenyl-pr...) Show SMILES Cn1cc(\C=C\C(=O)c2ccccc2)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H16N2O3/c1-19-12-13(11-15(19)8-10-17(21)18-22)7-9-16(20)14-5-3-2-4-6-14/h2-12,22H,1H3,(H,18,21)/b9-7+,10-8+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma"La Sapienza" Curated by ChEMBL					Assay Description Inhibitory concentration against maize histone deacetylase 2				J Med Chem 48: 3344-53 (2005) Article DOI: 10.1021/jm049002a BindingDB Entry DOI: 10.7270/Q2222VKN
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50134804 ((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-phenyl-pr...) Show SMILES Cn1cc(\C=C\C(=O)c2ccccc2)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H16N2O3/c1-19-12-13(11-15(19)8-10-17(21)18-22)7-9-16(20)14-5-3-2-4-6-14/h2-12,22H,1H3,(H,18,21)/b9-7+,10-8+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma"La Sapienza" Curated by ChEMBL					Assay Description Tested for maize Histone deacetylase 2 inhibitory activity				J Med Chem 46: 4826-9 (2003) Article DOI: 10.1021/jm034167p BindingDB Entry DOI: 10.7270/Q28C9X0G
					More data for this Ligand-Target Pair