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SMILES: CCn1c2cc3ncnc(N4CCN(CC4)C(=O)Nc4ccc(Oc5ccccc5)cc4)c3cc2n(C)c1=O

InChI Key: InChIKey=VJWMREWBGWVZIY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134846   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134846
PNG
(4-(3-Ethyl-1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4...)
Show SMILES CCn1c2cc3ncnc(N4CCN(CC4)C(=O)Nc4ccc(Oc5ccccc5)cc4)c3cc2n(C)c1=O
Show InChI InChI=1S/C29H29N7O3/c1-3-36-26-18-24-23(17-25(26)33(2)29(36)38)27(31-19-30-24)34-13-15-35(16-14-34)28(37)32-20-9-11-22(12-10-20)39-21-7-5-4-6-8-21/h4-12,17-19H,3,13-16H2,1-2H3,(H,32,37)
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Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair