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BDBM50134865 4-Quinolin-4-yl-piperazine-1-carbothioic acid benzylamide::CHEMBL144574

SMILES: S=C(NCc1ccccc1)N1CCN(CC1)c1ccnc2ccccc12

InChI Key: InChIKey=LOEZNTGLNUHGCD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134865   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50134865
PNG
(4-Quinolin-4-yl-piperazine-1-carbothioic acid benz...)
Show SMILES S=C(NCc1ccccc1)N1CCN(CC1)c1ccnc2ccccc12
Show InChI InChI=1S/C21H22N4S/c26-21(23-16-17-6-2-1-3-7-17)25-14-12-24(13-15-25)20-10-11-22-19-9-5-4-8-18(19)20/h1-11H,12-16H2,(H,23,26)
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MMDB

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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...


J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair