BDBM50134874 4-(6,7-Diethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-phenoxy-phenyl)-amide::CHEMBL144687

SMILES: CCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OCC

InChI Key: InChIKey=SWGWXWKAZGNYQO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50134874 (4-(6,7-Diethoxy-quinazolin-4-yl)-piperazine-1-carb...) Show SMILES CCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OCC Show InChI InChI=1S/C29H31N5O4/c1-3-36-26-18-24-25(19-27(26)37-4-2)30-20-31-28(24)33-14-16-34(17-15-33)29(35)32-21-10-12-23(13-11-21)38-22-8-6-5-7-9-22/h5-13,18-20H,3-4,14-17H2,1-2H3,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...				J Med Chem 46: 4910-25 (2003) Article DOI: 10.1021/jm020505v BindingDB Entry DOI: 10.7270/Q2X929PJ
					More data for this Ligand-Target Pair