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SMILES: COc1cc2cncc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC

InChI Key: InChIKey=FSNLVUZDIYPFFI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134878   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134878
PNG
(4-(6,7-Dimethoxy-isoquinolin-4-yl)-piperazine-1-ca...)
Show SMILES COc1cc2cncc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC
Show InChI InChI=1S/C28H28N4O4/c1-34-26-16-20-18-29-19-25(24(20)17-27(26)35-2)31-12-14-32(15-13-31)28(33)30-21-8-10-23(11-9-21)36-22-6-4-3-5-7-22/h3-11,16-19H,12-15H2,1-2H3,(H,30,33)
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MMDB

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Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair