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SMILES: COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)C#N)c2cc1O

InChI Key: InChIKey=FJBBGBKOTRTXKF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134884   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134884
PNG
(4-(6-Hydroxy-7-methoxy-quinazolin-4-yl)-piperazine...)
Show SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)C#N)c2cc1O
Show InChI InChI=1S/C21H20N6O3/c1-30-19-11-17-16(10-18(19)28)20(24-13-23-17)26-6-8-27(9-7-26)21(29)25-15-4-2-14(12-22)3-5-15/h2-5,10-11,13,28H,6-9H2,1H3,(H,25,29)
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UniChem

Similars
Article
PubMed
n/an/a 4.59E+3n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair