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SMILES: Clc1nnc(N2CCN(CC2)C(=O)Nc2ccc(Oc3ccccc3)cc2)c2ccccc12

InChI Key: InChIKey=OZOJGPUOXBKWKA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134893   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134893
PNG
(4-(4-Chloro-phthalazin-1-yl)-piperazine-1-carboxyl...)
Show SMILES Clc1nnc(N2CCN(CC2)C(=O)Nc2ccc(Oc3ccccc3)cc2)c2ccccc12
Show InChI InChI=1S/C25H22ClN5O2/c26-23-21-8-4-5-9-22(21)24(29-28-23)30-14-16-31(17-15-30)25(32)27-18-10-12-20(13-11-18)33-19-6-2-1-3-7-19/h1-13H,14-17H2,(H,27,32)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair