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SMILES: O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(CC1)c1cncc2ccccc12

InChI Key: InChIKey=HTCLUGKNEGLSGK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134896   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134896
PNG
(4-Isoquinolin-4-yl-piperazine-1-carboxylic acid (4...)
Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(CC1)c1cncc2ccccc12
Show InChI InChI=1S/C26H24N4O2/c31-26(28-21-10-12-23(13-11-21)32-22-7-2-1-3-8-22)30-16-14-29(15-17-30)25-19-27-18-20-6-4-5-9-24(20)25/h1-13,18-19H,14-17H2,(H,28,31)
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Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair