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SMILES: Clc1ccc2nccc(N3CCN(CC3)C(=S)NCc3ccccc3)c2c1

InChI Key: InChIKey=UIWVFPJOYNIQAH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134910   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134910
PNG
(4-(6-Chloro-quinolin-4-yl)-piperazine-1-carbothioi...)
Show SMILES Clc1ccc2nccc(N3CCN(CC3)C(=S)NCc3ccccc3)c2c1
Show InChI InChI=1S/C21H21ClN4S/c22-17-6-7-19-18(14-17)20(8-9-23-19)25-10-12-26(13-11-25)21(27)24-15-16-4-2-1-3-5-16/h1-9,14H,10-13,15H2,(H,24,27)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair