BDBM50135037 1-(2-(2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy)phenyl)-3-(naphthalen-1-yl)propan-1-one::1-{2-[2-Hydroxy-3-(4-hydroxy-4-phenyl-piperidin-1-yl)-propoxy]-phenyl}-3-naphthalen-1-yl-propan-1-one::CHEMBL147055

SMILES: OC(COc1ccccc1C(=O)CCc1cccc2ccccc12)CN1CCC(O)(CC1)c1ccccc1

InChI Key: InChIKey=NVSXFDQTCYVKHH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50135037 (1-(2-(2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-y...) Show SMILES OC(COc1ccccc1C(=O)CCc1cccc2ccccc12)CN1CCC(O)(CC1)c1ccccc1 Show InChI InChI=1S/C33H35NO4/c35-28(23-34-21-19-33(37,20-22-34)27-12-2-1-3-13-27)24-38-32-16-7-6-15-30(32)31(36)18-17-26-11-8-10-25-9-4-5-14-29(25)26/h1-16,28,35,37H,17-24H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay				J Med Chem 50: 1698-702 (2007) Article DOI: 10.1021/jm060604z BindingDB Entry DOI: 10.7270/Q2SB46JC
					More data for this Ligand-Target Pair