BDBM50135238 (S)-1-(2-Methyl-1H-indol-4-yloxy)-3-[(2S,4R)-2-methyl-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol::CHEMBL131370

SMILES: C[C@H]1C[C@@H](CCN1C[C@H](O)COc1cccc2[nH]c(C)cc12)c1cc2c(C)cccc2s1

InChI Key: InChIKey=ZRZHPXBPYCNVBE-HBMCJLEFSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50135238 ((S)-1-(2-Methyl-1H-indol-4-yloxy)-3-[(2S,4R)-2-met...) Show SMILES C[C@H]1C[C@@H](CCN1C[C@H](O)COc1cccc2[nH]c(C)cc12)c1cc2c(C)cccc2s1 Show InChI InChI=1S/C27H32N2O2S/c1-17-6-4-9-26-22(17)14-27(32-26)20-10-11-29(19(3)13-20)15-21(30)16-31-25-8-5-7-24-23(25)12-18(2)28-24/h4-9,12,14,19-21,28,30H,10-11,13,15-16H2,1-3H3/t19-,20+,21-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranes				Bioorg Med Chem Lett 13: 3939-42 (2003) BindingDB Entry DOI: 10.7270/Q24T6HSX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50135238 ((S)-1-(2-Methyl-1H-indol-4-yloxy)-3-[(2S,4R)-2-met...) Show SMILES C[C@H]1C[C@@H](CCN1C[C@H](O)COc1cccc2[nH]c(C)cc12)c1cc2c(C)cccc2s1 Show InChI InChI=1S/C27H32N2O2S/c1-17-6-4-9-26-22(17)14-27(32-26)20-10-11-29(19(3)13-20)15-21(30)16-31-25-8-5-7-24-23(25)12-18(2)28-24/h4-9,12,14,19-21,28,30H,10-11,13,15-16H2,1-3H3/t19-,20+,21-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 3939-42 (2003) BindingDB Entry DOI: 10.7270/Q24T6HSX
					More data for this Ligand-Target Pair