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SMILES: Cn1c2nc(Nc3cccc4[nH]ccc34)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=JFYFAAGDHKAZEG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135290   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PLK2


(Homo sapiens (Human))		BDBM50135290
PNG
(CHEMBL3745753)
Show SMILES Cn1c2nc(Nc3cccc4[nH]ccc34)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C22H16FN5O3S/c1-28-20-13(11-19(21(28)29)32(30,31)15-7-5-14(23)6-8-15)12-25-22(27-20)26-18-4-2-3-17-16(18)9-10-24-17/h2-12,24H,1H3,(H,25,26,27)
PDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 6.08E+3n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PLK2 using recombinant dephosphorylated bovine alpha- casein as substrate after 30 mins by scintillation counting ana...

Bioorg Med Chem 24: 521-44 (2016)


BindingDB Entry DOI: 10.7270/Q24Q7WT8
More data for this
Ligand-Target Pair