BDBM50135309 6-(2-Chloro-4-fluoro-phenylsulfanyl)-1-o-tolyl-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL128516

SMILES: Cc1ccccc1N1C(=O)NCc2nc(Sc3ccc(F)cc3Cl)ccc12

InChI Key: InChIKey=NMIPNOFQZFCFCK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50135309 (6-(2-Chloro-4-fluoro-phenylsulfanyl)-1-o-tolyl-3,4...) Show SMILES Cc1ccccc1N1C(=O)NCc2nc(Sc3ccc(F)cc3Cl)ccc12 Show InChI InChI=1S/C20H15ClFN3OS/c1-12-4-2-3-5-16(12)25-17-7-9-19(24-15(17)11-23-20(25)26)27-18-8-6-13(22)10-14(18)21/h2-10H,11H2,1H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 beta at 1000 nM				Bioorg Med Chem Lett 13: 3979-82 (2003) BindingDB Entry DOI: 10.7270/Q2RJ4HWB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50135309 (6-(2-Chloro-4-fluoro-phenylsulfanyl)-1-o-tolyl-3,4...) Show SMILES Cc1ccccc1N1C(=O)NCc2nc(Sc3ccc(F)cc3Cl)ccc12 Show InChI InChI=1S/C20H15ClFN3OS/c1-12-4-2-3-5-16(12)25-17-7-9-19(24-15(17)11-23-20(25)26)27-18-8-6-13(22)10-14(18)21/h2-10H,11H2,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 13: 3979-82 (2003) BindingDB Entry DOI: 10.7270/Q2RJ4HWB
					More data for this Ligand-Target Pair