BDBM50135405 CHEMBL334341::[5-(2,6-Diisopropyl-phenylcarbamoyl)-4-methyl-thiazol-2-yl]-carbamic acid tert-butyl ester

SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C

InChI Key: InChIKey=XZFCRBGZCHQFDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase LCK (Mus musculus)	BDBM50135405 (CHEMBL334341 | [5-(2,6-Diisopropyl-phenylcarbamoyl...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C Show InChI InChI=1S/C22H31N3O3S/c1-12(2)15-10-9-11-16(13(3)4)17(15)24-19(26)18-14(5)23-20(29-18)25-21(27)28-22(6,7)8/h9-13H,1-8H3,(H,24,26)(H,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of murine Lck kinase.				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair