BDBM50135408 CHEMBL128455::[5-(2,5-Dimethyl-1H-pyrrol-3-ylcarbamoyl)-4-methyl-thiazol-2-yl]-carbamic acid tert-butyl ester

SMILES: Cc1cc(NC(=O)c2sc(NC(=O)OC(C)(C)C)nc2C)c(C)[nH]1

InChI Key: InChIKey=PMVHGBYQXRZQHW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase LCK (Mus musculus)	BDBM50135408 (CHEMBL128455 | [5-(2,5-Dimethyl-1H-pyrrol-3-ylcarb...) Show SMILES Cc1cc(NC(=O)c2sc(NC(=O)OC(C)(C)C)nc2C)c(C)[nH]1 Show InChI InChI=1S/C16H22N4O3S/c1-8-7-11(9(2)17-8)19-13(21)12-10(3)18-14(24-12)20-15(22)23-16(4,5)6/h7,17H,1-6H3,(H,19,21)(H,18,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of murine Lck kinase.				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair