BDBM50135409 CHEMBL128795::[5-(2,2-Dimethyl-propylcarbamoyl)-4-methyl-thiazol-2-yl]-carbamic acid tert-butyl ester

SMILES: Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)NCC(C)(C)C

InChI Key: InChIKey=UQLIXZSRZAJXEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase LCK (Mus musculus)	BDBM50135409 (CHEMBL128795 | [5-(2,2-Dimethyl-propylcarbamoyl)-4...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)NCC(C)(C)C Show InChI InChI=1S/C15H25N3O3S/c1-9-10(11(19)16-8-14(2,3)4)22-12(17-9)18-13(20)21-15(5,6)7/h8H2,1-7H3,(H,16,19)(H,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of murine Lck kinase.				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair