BDBM50135509 5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic acid (2-methanesulfonyl-4-methoxymethyl-phenyl)-amide::CHEMBL132617

SMILES: COCc1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(c1)S(C)(=O)=O

InChI Key: InChIKey=RDROHJIRLHRNAR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50135509 (5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) Show SMILES COCc1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(c1)S(C)(=O)=O Show InChI InChI=1S/C18H18FNO5S3/c1-11-14-9-13(19)5-7-16(14)26-18(11)28(23,24)20-15-6-4-12(10-25-2)8-17(15)27(3,21)22/h4-9,20H,10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
Toa Eiyo Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human chymase				Bioorg Med Chem Lett 13: 4085-8 (2003) BindingDB Entry DOI: 10.7270/Q2QN665P
					More data for this Ligand-Target Pair