null

SMILES: Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O

InChI Key: InChIKey=FYKWNKRNOODGMT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50135777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Cotransfection activity of compound against human Peroxisome proliferator activated receptor gamma was determined				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determined				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory activity against human Peroxisome proliferator activated receptor alpha				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Cotransfection activity against human Peroxisome proliferator activated receptor alpha				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARdelta				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determined				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARalpha				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARgamma				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50135777 (2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...) Show SMILES Cn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C27H35N3O4/c1-26(2,3)21-14-10-20(11-15-21)18-30-25(33)29(6)23(28-30)9-7-8-19-12-16-22(17-13-19)34-27(4,5)24(31)32/h10-17H,7-9,18H2,1-6H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Cotransfection activity of compound against human Peroxisome proliferator activated receptor delta was determined				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair