BDBM50135877 (R)-2-(4-Chloro-2,6-dimethyl-phenoxy)-1-phenyl-ethylamine::(R)-2-(4-chloro-2,6-dimethylphenoxy)-1-phenylethanamine::CHEMBL356399

SMILES: Cc1cc(Cl)cc(C)c1OC[C@H](N)c1ccccc1

InChI Key: InChIKey=CBPCNTPWANLULL-HNNXBMFYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4) (Homo sapiens (Human))	BDBM50135877 ((R)-2-(4-Chloro-2,6-dimethyl-phenoxy)-1-phenyl-eth...) Show SMILES Cc1cc(Cl)cc(C)c1OC[C@H](N)c1ccccc1 |r| Show InChI InChI=1S/C16H18ClNO/c1-11-8-14(17)9-12(2)16(11)19-10-15(18)13-6-4-3-5-7-13/h3-9,15H,10,18H2,1-2H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium current				Eur J Med Chem 44: 1477-85 (2009) Article DOI: 10.1016/j.ejmech.2008.10.005 BindingDB Entry DOI: 10.7270/Q2M61MGC
					More data for this Ligand-Target Pair