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SMILES: CC1(C)N(CC#CCOCc2ccc(O)c(c2)C(N)=O)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=QBNJONOASBEBHT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135914   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Homo sapiens (Human))		BDBM50135914
PNG
(5-{4-[3-(4-Cyano-3-trifluoromethyl-phenyl)-5,5-dim...)
Show SMILES CC1(C)N(CC#CCOCc2ccc(O)c(c2)C(N)=O)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F
Show InChI InChI=1S/C25H21F3N4O5/c1-24(2)22(35)32(17-7-6-16(13-29)19(12-17)25(26,27)28)23(36)31(24)9-3-4-10-37-14-15-5-8-20(33)18(11-15)21(30)34/h5-8,11-12,33H,9-10,14H2,1-2H3,(H2,30,34)
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Similars
Article
PubMed
n/an/a 49n/an/an/an/an/an/a



University of Colorado

Curated by ChEMBL


Assay Description
Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysate

J Med Chem 46: 5258-70 (2003)


Article DOI: 10.1021/jm0303305
BindingDB Entry DOI: 10.7270/Q27D2VV7
More data for this
Ligand-Target Pair