null

SMILES: CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O

InChI Key: InChIKey=FUZLEHIZFGSVSF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50135934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasma				J Med Chem 46: 5294-7 (2003) Article DOI: 10.1021/jm034141y BindingDB Entry DOI: 10.7270/Q27H1J0Z
					More data for this Ligand-Target Pair
Carboxypeptidase A1 (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasma				J Med Chem 46: 5294-7 (2003) Article DOI: 10.1021/jm034141y BindingDB Entry DOI: 10.7270/Q27H1J0Z
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase A1 (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasma				J Med Chem 46: 5294-7 (2003) Article DOI: 10.1021/jm034141y BindingDB Entry DOI: 10.7270/Q27H1J0Z
					More data for this Ligand-Target Pair
Carboxypeptidase M (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasma				J Med Chem 46: 5294-7 (2003) Article DOI: 10.1021/jm034141y BindingDB Entry DOI: 10.7270/Q27H1J0Z
					More data for this Ligand-Target Pair
Carboxypeptidase M (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasma				J Med Chem 46: 5294-7 (2003) Article DOI: 10.1021/jm034141y BindingDB Entry DOI: 10.7270/Q27H1J0Z
					More data for this Ligand-Target Pair