BDBM50136430 5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-amide::CHEMBL134797

SMILES: Clc1ccc2[nH]c(cc2c1)C(=O)N[C@@H]1CCc2ccccc2NC1=O

InChI Key: InChIKey=VKSJJHHQYWOARV-MRXNPFEDSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscle glycogen phosphorylase (Homo sapiens (Human))	BDBM50136430 (5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,...) Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)N[C@@H]1CCc2ccccc2NC1=O Show InChI InChI=1S/C19H16ClN3O2/c20-13-6-8-15-12(9-13)10-17(21-15)19(25)23-16-7-5-11-3-1-2-4-14(11)22-18(16)24/h1-4,6,8-10,16,21H,5,7H2,(H,22,24)(H,23,25)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human muscle glycogen phosphorylase a (HMGPa)				Bioorg Med Chem Lett 13: 4385-8 (2003) BindingDB Entry DOI: 10.7270/Q2S75FQV
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50136430 (5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,...) Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)N[C@@H]1CCc2ccccc2NC1=O Show InChI InChI=1S/C19H16ClN3O2/c20-13-6-8-15-12(9-13)10-17(21-15)19(25)23-16-7-5-11-3-1-2-4-14(11)22-18(16)24/h1-4,6,8-10,16,21H,5,7H2,(H,22,24)(H,23,25)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Applied Science University Curated by ChEMBL					Assay Description Inhibition of human liver glycogen phosphorylase 1a assessed as release of phosphate from glucose-1- phosphate after 20 mins				Bioorg Med Chem 19: 4746-71 (2011) Article DOI: 10.1016/j.bmc.2011.06.086 BindingDB Entry DOI: 10.7270/Q2028RXJ
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50136430 (5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,...) Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)N[C@@H]1CCc2ccccc2NC1=O Show InChI InChI=1S/C19H16ClN3O2/c20-13-6-8-15-12(9-13)10-17(21-15)19(25)23-16-7-5-11-3-1-2-4-14(11)22-18(16)24/h1-4,6,8-10,16,21H,5,7H2,(H,22,24)(H,23,25)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa)				Bioorg Med Chem Lett 13: 4385-8 (2003) BindingDB Entry DOI: 10.7270/Q2S75FQV
					More data for this Ligand-Target Pair