BDBM50136434 7-Nitro-1H-indole-2-carboxylic acid (1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-amide::CHEMBL138822

SMILES: CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1

InChI Key: InChIKey=MUEAMCRYLFHEKE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50136434 (7-Nitro-1H-indole-2-carboxylic acid (1-methyl-2-ox...) Show SMILES CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1 Show InChI InChI=1S/C19H16N4O4/c1-22-15-7-3-2-5-11(15)9-14(19(22)25)21-18(24)13-10-12-6-4-8-16(23(26)27)17(12)20-13/h2-8,10,14,20H,9H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa)				Bioorg Med Chem Lett 13: 4385-8 (2003) BindingDB Entry DOI: 10.7270/Q2S75FQV
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50136434 (7-Nitro-1H-indole-2-carboxylic acid (1-methyl-2-ox...) Show SMILES CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1 Show InChI InChI=1S/C19H16N4O4/c1-22-15-7-3-2-5-11(15)9-14(19(22)25)21-18(24)13-10-12-6-4-8-16(23(26)27)17(12)20-13/h2-8,10,14,20H,9H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Applied Science University Curated by ChEMBL					Assay Description Inhibition of human liver glycogen phosphorylase 1a assessed as release of phosphate from glucose-1- phosphate after 20 mins				Bioorg Med Chem 19: 4746-71 (2011) Article DOI: 10.1016/j.bmc.2011.06.086 BindingDB Entry DOI: 10.7270/Q2028RXJ
					More data for this Ligand-Target Pair
Muscle glycogen phosphorylase (Homo sapiens (Human))	BDBM50136434 (7-Nitro-1H-indole-2-carboxylic acid (1-methyl-2-ox...) Show SMILES CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1 Show InChI InChI=1S/C19H16N4O4/c1-22-15-7-3-2-5-11(15)9-14(19(22)25)21-18(24)13-10-12-6-4-8-16(23(26)27)17(12)20-13/h2-8,10,14,20H,9H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human muscle glycogen phosphorylase a (HMGPa)				Bioorg Med Chem Lett 13: 4385-8 (2003) BindingDB Entry DOI: 10.7270/Q2S75FQV
					More data for this Ligand-Target Pair