BDBM50136721 4-(1-Benzhydryl-5-chloro-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid::CHEMBL343124

SMILES: COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12)C(O)=O

InChI Key: InChIKey=UMSGFRIPAMHGFC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50136721 (4-(1-Benzhydryl-5-chloro-1H-indol-3-ylmethyl)-3-me...) Show SMILES COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12)C(O)=O Show InChI InChI=1S/C30H24ClNO3/c1-35-28-17-23(30(33)34)13-12-22(28)16-24-19-32(27-15-14-25(31)18-26(24)27)29(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,17-19,29H,16H2,1H3,(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against cystolic phospholipase A2 alpha receptor (c-PLA2 alpha) using coumarin assay				Bioorg Med Chem Lett 13: 4501-4 (2003) BindingDB Entry DOI: 10.7270/Q2W095BN
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50136721 (4-(1-Benzhydryl-5-chloro-1H-indol-3-ylmethyl)-3-me...) Show SMILES COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12)C(O)=O Show InChI InChI=1S/C30H24ClNO3/c1-35-28-17-23(30(33)34)13-12-22(28)16-24-19-32(27-15-14-25(31)18-26(24)27)29(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,17-19,29H,16H2,1H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against LTB4 receptor determined in human neutrophils PMN assay				Bioorg Med Chem Lett 13: 4501-4 (2003) BindingDB Entry DOI: 10.7270/Q2W095BN
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50136721 (4-(1-Benzhydryl-5-chloro-1H-indol-3-ylmethyl)-3-me...) Show SMILES COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12)C(O)=O Show InChI InChI=1S/C30H24ClNO3/c1-35-28-17-23(30(33)34)13-12-22(28)16-24-19-32(27-15-14-25(31)18-26(24)27)29(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,17-19,29H,16H2,1H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against LTB4 receptor determined in human neutrophils PMN assay				Bioorg Med Chem Lett 13: 4501-4 (2003) BindingDB Entry DOI: 10.7270/Q2W095BN
					More data for this Ligand-Target Pair