BDBM50136784 6-amino-18-(4-aminobutyl)-9,24-dibenzyl-12-(4-hydroxybenzyl)-21-(1-hydroxyethyl)-15-(1-naphthylmethyl)-7,10,13,16,19,22,25-heptaoxo-3,4-dithia-8,11,14,17,20,23,26-heptaazacyclohexacosane-1-carboxylic acid::CHEMBL414916
SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)C(Cc2cccc3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O
InChI Key: InChIKey=WNXUROSSCSHIHM-MWVPSNCISA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50136784 (6-amino-18-(4-aminobutyl)-9,24-dibenzyl-12-(4-hydr...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity at human Somatostatin receptor type 5 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement. | J Med Chem 46: 5587-96 (2003) Article DOI: 10.1021/jm0302445 BindingDB Entry DOI: 10.7270/Q2FX7B50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50136784 (6-amino-18-(4-aminobutyl)-9,24-dibenzyl-12-(4-hydr...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity at human Somatostatin receptor type 3 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement. | J Med Chem 46: 5587-96 (2003) Article DOI: 10.1021/jm0302445 BindingDB Entry DOI: 10.7270/Q2FX7B50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50136784 (6-amino-18-(4-aminobutyl)-9,24-dibenzyl-12-(4-hydr...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement. | J Med Chem 46: 5587-96 (2003) Article DOI: 10.1021/jm0302445 BindingDB Entry DOI: 10.7270/Q2FX7B50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50136784 (6-amino-18-(4-aminobutyl)-9,24-dibenzyl-12-(4-hydr...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity at human Somatostatin receptor type 2 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement. | J Med Chem 46: 5587-96 (2003) Article DOI: 10.1021/jm0302445 BindingDB Entry DOI: 10.7270/Q2FX7B50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50136784 (6-amino-18-(4-aminobutyl)-9,24-dibenzyl-12-(4-hydr...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity at human Somatostatin receptor type 4 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement. | J Med Chem 46: 5587-96 (2003) Article DOI: 10.1021/jm0302445 BindingDB Entry DOI: 10.7270/Q2FX7B50 | |||||||||||
More data for this Ligand-Target Pair |