BDBM50136800 (4R,7S,10R,13S,16S,19S,22R,25S)-25-Amino-13-(4-amino-butyl)-19,22-dibenzyl-7-(4-hydroxy-benzyl)-10-((R)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacosane-4-carboxylic acid::CHEMBL407025
SMILES: C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(O)=O
InChI Key: InChIKey=UCNKQLMKTJDSDK-COQPDMAFSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50136800 ((4R,7S,10R,13S,16S,19S,22R,25S)-25-Amino-13-(4-ami...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity towards human somatostatin receptor type 4 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand. | J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50136800 ((4R,7S,10R,13S,16S,19S,22R,25S)-25-Amino-13-(4-ami...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity towards human somatostatin receptor type 5 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand. | J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50136800 ((4R,7S,10R,13S,16S,19S,22R,25S)-25-Amino-13-(4-ami...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity towards human somatostatin receptor type 1 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand. | J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50136800 ((4R,7S,10R,13S,16S,19S,22R,25S)-25-Amino-13-(4-ami...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity towards human somatostatin receptor type 3 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand. | J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50136800 ((4R,7S,10R,13S,16S,19S,22R,25S)-25-Amino-13-(4-ami...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Binding affinity towards human somatostatin receptor type 2 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand. | J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X | |||||||||||
More data for this Ligand-Target Pair |