BDBM50136896 CHEMBL356157::[4-(2-Amino-phenylamino)-3-methyl-phenyl]-o-tolyl-methanone

SMILES: Cc1ccccc1C(=O)c1ccc(Nc2ccccc2N)c(C)c1

InChI Key: InChIKey=ZTCSEBJFMIAPGW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50136896 (CHEMBL356157 | [4-(2-Amino-phenylamino)-3-methyl-p...) Show SMILES Cc1ccccc1C(=O)c1ccc(Nc2ccccc2N)c(C)c1 Show InChI InChI=1S/C21H20N2O/c1-14-7-3-4-8-17(14)21(24)16-11-12-19(15(2)13-16)23-20-10-6-5-9-18(20)22/h3-13,23H,22H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma Curated by ChEMBL					Assay Description In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alpha				J Med Chem 46: 5651-62 (2003) Article DOI: 10.1021/jm030851s BindingDB Entry DOI: 10.7270/Q2B56KFK
					More data for this Ligand-Target Pair