BDBM50136922 CHEMBL346924::N-(3-Chloro-7-isobutylamino-1H-indazol-5-yl)-3-(2-methyl-pyridin-4-yl)-benzenesulfonamide

SMILES: CC(C)CNc1cc(NS(=O)(=O)c2cccc(c2)-c2ccnc(C)c2)cc2c(Cl)[nH]nc12

InChI Key: InChIKey=PPEKMCUUWOJPKO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12))	BDBM50136922 (CHEMBL346924 | N-(3-Chloro-7-isobutylamino-1H-inda...) Show SMILES CC(C)CNc1cc(NS(=O)(=O)c2cccc(c2)-c2ccnc(C)c2)cc2c(Cl)[nH]nc12 Show InChI InChI=1S/C23H24ClN5O2S/c1-14(2)13-26-21-12-18(11-20-22(21)27-28-23(20)24)29-32(30,31)19-6-4-5-16(10-19)17-7-8-25-15(3)9-17/h4-12,14,26,29H,13H2,1-3H3,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Quorex Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)				J Med Chem 46: 5663-73 (2003) Article DOI: 10.1021/jm0302039 BindingDB Entry DOI: 10.7270/Q279443D
					More data for this Ligand-Target Pair