BDBM50137101 1-(7-Formylamino-5,8-dioxo-5,8-dihydro-quinolin-2-yl)-9H-beta-carboline-3-carboxylic acid amide::CHEMBL154000

SMILES: NC(=O)c1cc2c3ccccc3[nH]c2c(n1)-c1ccc2C(=O)C=C(NC=O)C(=O)c2n1

InChI Key: InChIKey=MQPRWEQHZCQWIF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50137101 (1-(7-Formylamino-5,8-dioxo-5,8-dihydro-quinolin-2-...) Show SMILES NC(=O)c1cc2c3ccccc3[nH]c2c(n1)-c1ccc2C(=O)C=C(NC=O)C(=O)c2n1 |t:25| Show InChI InChI=1S/C22H13N5O4/c23-22(31)16-7-12-10-3-1-2-4-13(10)25-18(12)20(27-16)14-6-5-11-17(29)8-15(24-9-28)21(30)19(11)26-14/h1-9,25H,(H2,23,31)(H,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ball State University Curated by ChEMBL					Assay Description Inhibitory activity against HIV-reverse transcriptase (HIV-RT)				J Med Chem 46: 5773-80 (2003) Article DOI: 10.1021/jm0304414 BindingDB Entry DOI: 10.7270/Q2QC02WD
					More data for this Ligand-Target Pair