BDBM50137183 (3-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4-yl)-amine::CHEMBL310827

SMILES: Cc1c[nH]c2ccc(Nc3ncnc4cc(sc34)-c3ccccc3)cc12

InChI Key: InChIKey=RDSINGBRTMDIHM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50137183 ((3-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...) Show SMILES Cc1c[nH]c2ccc(Nc3ncnc4cc(sc34)-c3ccccc3)cc12 Show InChI InChI=1S/C21H16N4S/c1-13-11-22-17-8-7-15(9-16(13)17)25-21-20-18(23-12-24-21)10-19(26-20)14-5-3-2-4-6-14/h2-12,22H,1H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against epidermal growth factor receptor				Bioorg Med Chem Lett 14: 21-4 (2003) BindingDB Entry DOI: 10.7270/Q2FT8KFT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50137183 ((3-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...) Show SMILES Cc1c[nH]c2ccc(Nc3ncnc4cc(sc34)-c3ccccc3)cc12 Show InChI InChI=1S/C21H16N4S/c1-13-11-22-17-8-7-15(9-16(13)17)25-21-20-18(23-12-24-21)10-19(26-20)14-5-3-2-4-6-14/h2-12,22H,1H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against Vascular endothelial growth factor receptor				Bioorg Med Chem Lett 14: 21-4 (2003) BindingDB Entry DOI: 10.7270/Q2FT8KFT
					More data for this Ligand-Target Pair