BDBM50137201 CHEMBL77782::{6-[4-(2-Dimethylamino-ethyl)-phenyl]-thieno[3,2-d]pyrimidin-4-yl}-(1H-indol-5-yl)-amine

SMILES: CN(C)CCc1ccc(cc1)-c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1

InChI Key: InChIKey=IXKNBAGOTATIPL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50137201 (CHEMBL77782 | {6-[4-(2-Dimethylamino-ethyl)-phenyl...) Show SMILES CN(C)CCc1ccc(cc1)-c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1 Show InChI InChI=1S/C24H23N5S/c1-29(2)12-10-16-3-5-17(6-4-16)22-14-21-23(30-22)24(27-15-26-21)28-19-7-8-20-18(13-19)9-11-25-20/h3-9,11,13-15,25H,10,12H2,1-2H3,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against Vascular endothelial growth factor receptor				Bioorg Med Chem Lett 14: 21-4 (2003) BindingDB Entry DOI: 10.7270/Q2FT8KFT
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50137201 (CHEMBL77782 | {6-[4-(2-Dimethylamino-ethyl)-phenyl...) Show SMILES CN(C)CCc1ccc(cc1)-c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1 Show InChI InChI=1S/C24H23N5S/c1-29(2)12-10-16-3-5-17(6-4-16)22-14-21-23(30-22)24(27-15-26-21)28-19-7-8-20-18(13-19)9-11-25-20/h3-9,11,13-15,25H,10,12H2,1-2H3,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against epidermal growth factor receptor				Bioorg Med Chem Lett 14: 21-4 (2003) BindingDB Entry DOI: 10.7270/Q2FT8KFT
					More data for this Ligand-Target Pair