BindingDB PrimarySearch

BDBM50137277 2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL148406

SMILES: Nc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)ccc2C1C(=O)NO

InChI Key: InChIKey=VVZFBVIPGIVQRI-UHFFFAOYSA-N

Data: 8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137277
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	835	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-14 (MMP-14)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-9 (MMP-9)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-1 (MMP-1)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase 15 (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-15 (MMP-15)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase 26 (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	492	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-26 (MMP-26)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-12 (MMP-12)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-2 (MMP-2)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase 16 (Homo sapiens (Human))	BDBM50137277 (2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-16 (MMP-16)				Bioorg Med Chem Lett 14: 47-50 (2003) BindingDB Entry DOI: 10.7270/Q22J6B79
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair