BDBM50137451 CHEMBL3753587

SMILES: OCc1ccc(cc1)-c1ccc(s1)-c1ccc2C(=O)OCc2c1

InChI Key: InChIKey=JVYDJHPQTXVJJZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Perforin-1 (Homo sapiens (Human))	BDBM50137451 (CHEMBL3753587) Show SMILES OCc1ccc(cc1)-c1ccc(s1)-c1ccc2C(=O)OCc2c1 Show InChI InChI=1S/C19H14O3S/c20-10-12-1-3-13(4-2-12)17-7-8-18(23-17)14-5-6-16-15(9-14)11-22-19(16)21/h1-9,20H,10-11H2	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati...				Bioorg Med Chem Lett 26: 355-60 (2016) BindingDB Entry DOI: 10.7270/Q2B859ZN
					More data for this Ligand-Target Pair