BDBM50137456 CHEMBL3753271
SMILES: NC(=O)c1ccc(cn1)-c1ccc(s1)-c1ccc2C(=O)OCc2c1
InChI Key: InChIKey=ZHXKLRNCGNSIRI-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Perforin-1 (Homo sapiens (Human)) | BDBM50137456 (CHEMBL3753271) | NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati... | Bioorg Med Chem Lett 26: 355-60 (2016) BindingDB Entry DOI: 10.7270/Q2B859ZN | |||||||||||
More data for this Ligand-Target Pair |