BDBM50137468 1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-carboxylic acid 3,4-dimethoxy-benzylamide::CHEMBL366941

SMILES: COc1ccc(CNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC

InChI Key: InChIKey=BHTRHXPOZQPPSK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137468 (1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...) Show SMILES COc1ccc(CNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC Show InChI InChI=1S/C28H30N4O3/c1-34-25-14-11-19(16-26(25)35-2)18-30-28(33)20-12-13-24-23(17-20)31-27(22-10-6-7-15-29-22)32(24)21-8-4-3-5-9-21/h6-7,10-17,21H,3-5,8-9,18H2,1-2H3,(H,30,33)	B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against NS5B polymerase of hepatitis C virus				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair
Poliovirus type 1 polyprotein (Poliovirus type 1 (strain Mahoney))	BDBM50137468 (1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...) Show SMILES COc1ccc(CNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC Show InChI InChI=1S/C28H30N4O3/c1-34-25-14-11-19(16-26(25)35-2)18-30-28(33)20-12-13-24-23(17-20)31-27(22-10-6-7-15-29-22)32(24)21-8-4-3-5-9-21/h6-7,10-17,21H,3-5,8-9,18H2,1-2H3,(H,30,33)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against polio virus RNA polymerase				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137468 (1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...) Show SMILES COc1ccc(CNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC Show InChI InChI=1S/C28H30N4O3/c1-34-25-14-11-19(16-26(25)35-2)18-30-28(33)20-12-13-24-23(17-20)31-27(22-10-6-7-15-29-22)32(24)21-8-4-3-5-9-21/h6-7,10-17,21H,3-5,8-9,18H2,1-2H3,(H,30,33)	B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.				Bioorg Med Chem Lett 14: 967-71 (2004) Article DOI: 10.1016/j.bmcl.2003.12.032 BindingDB Entry DOI: 10.7270/Q29C6WVF
					More data for this Ligand-Target Pair