BDBM50137538 2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-furo[3,2-b]pyridin-5-yl]-benzamide::CHEMBL177238
SMILES: CN1CCC(CC1)c1coc2ccc(NC(=O)c3ccc(F)cc3Cl)nc12
InChI Key: InChIKey=IWNPMSHFWIZUSM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50137538 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50137538 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 277 | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair |