BDBM50137590 3-[1-[3-(3-Dimethylamino-propyl)-4,5,6,7-tetrahydro-1H-indol-2-yl]-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one::CHEMBL293595

SMILES: COc1ccc2NC(=O)\C(=C/c3[nH]c4CCCCc4c3CCCN(C)C)c2c1

InChI Key: InChIKey=BPURWUGKIYEJOT-RGEXLXHISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50137590 (3-[1-[3-(3-Dimethylamino-propyl)-4,5,6,7-tetrahydr...) Show SMILES COc1ccc2NC(=O)\C(=C/c3[nH]c4CCCCc4c3CCCN(C)C)c2c1 Show InChI InChI=1S/C23H29N3O2/c1-26(2)12-6-8-17-16-7-4-5-9-20(16)24-22(17)14-19-18-13-15(28-3)10-11-21(18)25-23(19)27/h10-11,13-14,24H,4-9,12H2,1-3H3,(H,25,27)/b19-14-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Src protein tryrosine kinase				Bioorg Med Chem Lett 14: 187-90 (2003) BindingDB Entry DOI: 10.7270/Q2HM57VG
					More data for this Ligand-Target Pair