BDBM50137638 CHEMBL3753705

SMILES: CN1CCN(CC1)c1nc2CCc3ccccc3-c2c(n1)N1CCN(C)CC1

InChI Key: InChIKey=MUIFBAAAIAZNFI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50137638 (CHEMBL3753705) Show SMILES CN1CCN(CC1)c1nc2CCc3ccccc3-c2c(n1)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6/c1-25-9-13-27(14-10-25)21-20-18-6-4-3-5-17(18)7-8-19(20)23-22(24-21)28-15-11-26(2)12-16-28/h3-6H,7-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from human histamine 1 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50137638 (CHEMBL3753705) Show SMILES CN1CCN(CC1)c1nc2CCc3ccccc3-c2c(n1)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6/c1-25-9-13-27(14-10-25)21-20-18-6-4-3-5-17(18)7-8-19(20)23-22(24-21)28-15-11-26(2)12-16-28/h3-6H,7-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair