BDBM50137645 CHEMBL3752383

SMILES: CN1CCN(CC1)c1cc(nc(NCCc2ccccc2)n1)-c1ccccc1

InChI Key: InChIKey=RJBSDPQABLYGGQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50137645 (CHEMBL3752383) Show SMILES CN1CCN(CC1)c1cc(nc(NCCc2ccccc2)n1)-c1ccccc1 Show InChI InChI=1S/C23H27N5/c1-27-14-16-28(17-15-27)22-18-21(20-10-6-3-7-11-20)25-23(26-22)24-13-12-19-8-4-2-5-9-19/h2-11,18H,12-17H2,1H3,(H,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from human histamine 1 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50137645 (CHEMBL3752383) Show SMILES CN1CCN(CC1)c1cc(nc(NCCc2ccccc2)n1)-c1ccccc1 Show InChI InChI=1S/C23H27N5/c1-27-14-16-28(17-15-27)22-18-21(20-10-6-3-7-11-20)25-23(26-22)24-13-12-19-8-4-2-5-9-19/h2-11,18H,12-17H2,1H3,(H,24,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair