BDBM50137646 CHEMBL3752195

SMILES: COc1ccc(CNc2nc(cc(n2)-c2ccccc2)N2CCN(C)CC2)cc1

InChI Key: InChIKey=ZJMSFLXJAVTTGF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50137646 (CHEMBL3752195) Show SMILES COc1ccc(CNc2nc(cc(n2)-c2ccccc2)N2CCN(C)CC2)cc1 Show InChI InChI=1S/C23H27N5O/c1-27-12-14-28(15-13-27)22-16-21(19-6-4-3-5-7-19)25-23(26-22)24-17-18-8-10-20(29-2)11-9-18/h3-11,16H,12-15,17H2,1-2H3,(H,24,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50137646 (CHEMBL3752195) Show SMILES COc1ccc(CNc2nc(cc(n2)-c2ccccc2)N2CCN(C)CC2)cc1 Show InChI InChI=1S/C23H27N5O/c1-27-12-14-28(15-13-27)22-16-21(19-6-4-3-5-7-19)25-23(26-22)24-17-18-8-10-20(29-2)11-9-18/h3-11,16H,12-15,17H2,1-2H3,(H,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from human histamine 1 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair