BDBM50137654 CHEMBL3754176

SMILES: CN1CCN(CC1)c1nc(NCc2ccc(C)cc2)nc-2c1CCc1ccccc-21

InChI Key: InChIKey=DASXSVINLZRITJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50137654 (CHEMBL3754176) Show SMILES CN1CCN(CC1)c1nc(NCc2ccc(C)cc2)nc-2c1CCc1ccccc-21 Show InChI InChI=1S/C25H29N5/c1-18-7-9-19(10-8-18)17-26-25-27-23-21-6-4-3-5-20(21)11-12-22(23)24(28-25)30-15-13-29(2)14-16-30/h3-10H,11-17H2,1-2H3,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from human histamine 1 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50137654 (CHEMBL3754176) Show SMILES CN1CCN(CC1)c1nc(NCc2ccc(C)cc2)nc-2c1CCc1ccccc-21 Show InChI InChI=1S/C25H29N5/c1-18-7-9-19(10-8-18)17-26-25-27-23-21-6-4-3-5-20(21)11-12-22(23)24(28-25)30-15-13-29(2)14-16-30/h3-10H,11-17H2,1-2H3,(H,26,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair